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MYP_126178
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Basic Information
LSer-Def4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
34 amino acids
C171H282N54O42S6
Standard
Sequence
LTCNIDRSFCLAHCLLRGYKRGFCTVKKICVCRH
Physicochemical Analysis
3958.80 Da
9.38
5.87
5.47
0.1727
0.22
0.72
-0.07
59.62
88.82
0.0882
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1567.95
-14.24
64.0
56.0
132.0
273.0
5.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0221529 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
LSer
13632
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperAntimicrob Agents Chemother. 2015 May;59(5):2508-14 | http://www.ncbi.nlm.nih.gov/pubmed/25666157 PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0254224 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
13632
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Micrococcus luteus
38.8 μM
MIC
PaperAntimicrobial peptides expressed in medicinal maggots of the blow fly Lucilia sericata show combinatorial activity against bacteria. PMID25666157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25666157/
RECORD: Rec_0405922 VERIFIED: YES
Provenance & Taxonomy
Lucilia cuprina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0408539 VERIFIED: YES
Provenance & Taxonomy
Lucilia sericata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
100 μM
MIC
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