Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC553H881N145O166S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHITAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLDNTGHTAIALTSCRTTSGDIDIKLSGKS
    

Molecular Weight12312.98 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.12

Hydrophobic Moment 0.53

Boman Index0.15

Instability Index21.32

Aliphatic Index 95.79

Aromaticity 0.0877

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4973.55

LogP -53.37

H-bond Donors 179.0

H-bond Acceptors 174.0

Rotatable Bonds 405.0

Heavy Atoms 867.0

Ring Count 18.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374998 VERIFIED: NO

Provenance & Taxonomy

OrganismCircaetus pectoralis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria