Peptide Database

Peptide NameL-amino-acid oxidase ACTX-8 (LAAO) (LAO) (EC 1.4.3.2)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC104H150N28O38

DescriptionStandard

        ADDRNPLEEFRENNYEEFL
    

Molecular Weight2400.47 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.19

Net Charge (pH 7.4) -5.39

Charge Density (pH 7.0) -0.2731

GRAVY Index-1.68

Hydrophobic Moment 0.48

Boman Index-0.39

Instability Index36.36

Aliphatic Index 46.32

Aromaticity 0.1579

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1112.73

LogP -10.40

H-bond Donors 36.0

H-bond Acceptors 33.0

Rotatable Bonds 79.0

Heavy Atoms 170.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057109 VERIFIED: YES

Provenance & Taxonomy

OrganismDeinagkistrodon acutus [Animal]

FamilyFlavin monoamine oxidase; FIG1 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Oxidoreductase Cytolytic Toxin Anticancer Hemolytic

RECORD: Rec_0086591 VERIFIED: YES

Provenance & Taxonomy

OrganismDeinagkistrodon acutus [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anticancer Antiparasitic

RECORD: Rec_0161730 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0243436 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 21.1%, E 0.0%, T 21.1%, C 57.9% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic