Peptide Database

Peptide Nametau-Theraphotoxin-Pc1b

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC164H240N44O50S7

DescriptionStandard

        GACRWFLGGCKSTSDCCEHLSCKMGLDYCAWDGTF
    

Molecular Weight3852.38 Da

Isoelectric Point (pI)5.43

Net Charge (pH 7.0)-1.21

Net Charge (pH 7.4) -1.56

Charge Density (pH 7.0) -0.0345

GRAVY Index-0.03

Hydrophobic Moment 0.50

Boman Index0.10

Instability Index57.31

Aliphatic Index 39.14

Aromaticity 0.1429

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1497.50

LogP -16.06

H-bond Donors 60.0

H-bond Acceptors 57.0

Rotatable Bonds 122.0

Heavy Atoms 265.0

Ring Count 8.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057960 VERIFIED: NO

Provenance & Taxonomy

OrganismPsalmopoeus cambridgei [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide3-17; 10-22; 16-29

Bio-Activity Profile

Function

Toxin

TargetTRPV1

RECORD: Rec_0161521 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic