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MYP_126032
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Basic Information
Mitoparan [L14S], Mastoparan [A5,8K;A10Aib;L14S]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
INLKKLAKLXKKIS
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0165379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical amino-acid peptide containing Aib [Modified]
Amidation
Aib (α-aminoisobutyric acid) at position 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human astrocytoma U373-MG
30 μM
Cell viability/cytotoxicity assay
PaperAntimicrobial and anticancer activity of the synthetic peptide [Ser14]Mitoparan. Peptides. 2018. DOI:10.1016/j.peptides.2018.01.007. PMID:29337270. PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0179579 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical amino-acid peptide containing Aib [Modified]
Amidation
Aib (α-aminoisobutyric acid) at position 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii
32 μg/mL
MIC
PaperAntimicrobial and anticancer activity of the synthetic peptide [Ser14]Mitoparan. Peptides. 2018. DOI:10.1016/j.peptides.2018.01.007. PMID:29337270. PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0248799 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical amino-acid peptide containing Aib [Modified]
Amidation
Aib (α-aminoisobutyric acid) at position 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
32 μg/mL
MIC
PaperAntimicrobial and anticancer activity of the synthetic peptide [Ser14]Mitoparan. Peptides. 2018. DOI:10.1016/j.peptides.2018.01.007. PMID:29337270. PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0371512 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical amino-acid peptide containing Aib [Modified]
Amidation
Aib (α-aminoisobutyric acid) at position 10
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Cryptococcus neoformans
5.33 μg/mL
MIC
PaperAntimicrobial and anticancer activity of the synthetic peptide [Ser14]Mitoparan. Peptides. 2018. DOI:10.1016/j.peptides.2018.01.007. PMID:29337270. PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
RECORD: Rec_0426182 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical amino-acid peptide containing Aib [Modified]
Amidation
Aib (α-aminoisobutyric acid) at position 10
Bio-Activity Profile
Cytotoxic
Human embryonic kidney HEK293 cells
>32 μg/mL
Cytotoxicity
PaperAntimicrobial and anticancer activity of the synthetic peptide [Ser14]Mitoparan. Peptides. 2018. DOI:10.1016/j.peptides.2018.01.007. PMID:29337270. PMID29337270 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29337270/
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