‹ ›
MYP_126026
← PREVIOUS NEXT → BACK
Basic Information
Anti-lipopolysaccharide factor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
101 amino acids
C537H816N152O146S2
Standard
Sequence
DGIWTQLIFTLVKNLATLWQSGDFQFLDHECHYRIKPTFRRLKWKYKGKFWCPSWTSITGRATKSSRSGAVEHSVRNFVGQAKSSGLITQRQAEQFISQYN
Physicochemical Analysis
11801.28 Da
10.09
9.00
8.60
0.0891
-0.55
0.62
-0.07
37.12
66.63
0.1485
31970.00
32095.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4884.81
-47.83
177.0
160.0
390.0
837.0
25.0
111.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0021011 VERIFIED: NO
Provenance & Taxonomy
Limulus polyphemus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-negative Hemolytic Non-ribosomal
Gram-negative bacteria
Qualitative functional evidence
PMID3667549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3667549/; https://www.uniprot.org/uniprotkb/P07086/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0106654 VERIFIED: NO
Provenance & Taxonomy
Limulus polyphemus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperLALF Evidence URLhttps://www.uniprot.org/uniprotkb/P07086/entry
RECORD: Rec_0244244 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperHoess A., Watson S., Siber G.R., Liddington R.;. "Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5-A resolution."; EMBO J. 12:3351-3356. Evidence URLhttps://www.uniprot.org/uniprotkb/ALPS_LIMPO/entry
RECORD: Rec_0361108 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
LALF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PaperJ Biochem. 1987 Jun;101(6):1321-30. | http://www.ncbi.nlm.nih.gov/pubmed/3667549 PMID3667549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3667549/
RECORD: Rec_0362072 VERIFIED: YES
Provenance & Taxonomy
Limulus polyphemus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
31-52
Bio-Activity Profile
Antimicrobial
S. minnesota R595
PaperIsolation and biological activities of limulus anticoagulant (anti-LPS factor) which interacts with lipopolysaccharide (LPS).