Peptide Database

Peptide NameDermaseptin-PH (DRS-PH)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC349H573N93O114S4

DescriptionStandard

        MDILKKSLFLILFLGVVSLSICEEEKRENEEEMEQDDEQSEMKRALWKEVLKNAGKAALNEINNLVQGGQ
    

Molecular Weight8024.10 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-6.48

Net Charge (pH 7.4) -6.74

Charge Density (pH 7.0) -0.0926

GRAVY Index-0.46

Hydrophobic Moment 0.66

Boman Index-0.07

Instability Index64.84

Aliphatic Index 100.29

Aromaticity 0.0429

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3421.18

LogP -30.24

H-bond Donors 114.0

H-bond Acceptors 112.0

Rotatable Bonds 291.0

Heavy Atoms 560.0

Ring Count 4.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074266 VERIFIED: NO

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function