Peptide Database

Peptide NameFMRFamide-related peptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC58H83N17O17

DescriptionStandard

        GYSDRNYLRF
    

Molecular Weight1290.38 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0759

GRAVY Index-1.32

Hydrophobic Moment 0.45

Boman Index-0.37

Instability Index24.57

Aliphatic Index 39.00

Aromaticity 0.3000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 590.10

LogP -5.55

H-bond Donors 22.0

H-bond Acceptors 18.0

Rotatable Bonds 40.0

Heavy Atoms 92.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104927 VERIFIED: YES

Provenance & Taxonomy

OrganismHomarus americanus [Animal]

FamilyFMRFamide-related peptide

Tax ID6706

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0198706 VERIFIED: NO

Provenance & Taxonomy

OrganismHomarus americanus [Animal] [Animal]; Paranephrops zealandicus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0294020 VERIFIED: YES

Provenance & Taxonomy

OrganismHomarus americanus [Animal]

FamilyFMRFamide related peptide

Tax ID6706

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0399113 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/