Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 1

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC216H363N63O62S10

DescriptionStandard

        ETLFTANCLDRKDCKKHCKSKGCKEMKCEQIIKPTWRCLCIMCS
    

Molecular Weight5155.23 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.49

Charge Density (pH 7.0) 0.1101

GRAVY Index-0.48

Hydrophobic Moment 0.68

Boman Index-0.22

Instability Index11.55

Aliphatic Index 55.45

Aromaticity 0.0455

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2056.09

LogP -20.07

H-bond Donors 80.0

H-bond Acceptors 78.0

Rotatable Bonds 181.0

Heavy Atoms 351.0

Ring Count 5.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367461 VERIFIED: NO

Provenance & Taxonomy

OrganismHadrurus gertschi [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Channel blocker

TargetKv1.1/KCNA1, Kv1.2/KCNA2, Kv1.3/KCNA3