Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length269 amino acids

Chemical FormulaC1341H2114N386O385S8

DescriptionStandard

        MRIHHFLLRNSQLSLHPRQGIKASLSNNHVSVSGNWKVKKSFITLHGTFDLSVDGMSILVSLNLDKDQSGRPTVSVTHCHNSIGHVSIEISGHISWILNLFHERIENNVKNILEQKICKMVKESAASRLEPYLRTLPVTSMIDQIAGIDYRLVGAPQVTFQGLDTPFKGEFFGRNWNSSVPFDAPPITLPQKNDHMIYFAVSEYVFNTASRVYHQAGQMKFTIQNKHVSRGGKRLGVPGEKIRWDSRSTVSALGSQEKNVAFGASQIGV
    

Molecular Weight30060.00 Da

Isoelectric Point (pI)9.72

Net Charge (pH 7.0)10.63

Net Charge (pH 7.4) 9.67

Charge Density (pH 7.0) 0.0395

GRAVY Index-0.26

Hydrophobic Moment 0.84

Boman Index0.02

Instability Index45.90

Aliphatic Index 87.62

Aromaticity 0.0818

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0149171 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus grunniens (Wild yak) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria