Peptide Database

Peptide NameVenom serine protease inhibitor (AcVSPI) (VSPI) (Allergen Api m 6-like peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC434H703N127O105S11

DescriptionStandard

        MPRLVLVSFLFLAIFSVFIGGFAKSKCPRNEIFTRCHAACQPSCARLARKPFCIKICKPGCICTSGYLRNKNNVCVPRSRCFSGRLL
    

Molecular Weight9732.73 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)13.48

Net Charge (pH 7.4) 13.06

Charge Density (pH 7.0) 0.1550

GRAVY Index0.35

Hydrophobic Moment 0.62

Boman Index0.05

Instability Index51.97

Aliphatic Index 86.32

Aromaticity 0.1034

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3710.13

LogP -34.28

H-bond Donors 142.0

H-bond Acceptors 131.0

Rotatable Bonds 316.0

Heavy Atoms 677.0

Ring Count 16.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049458 VERIFIED: YES

Provenance & Taxonomy

OrganismApis cerana [Animal]

FamilySerine protease inhibitor-like (TIL domain-containing)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Protease inhibitor Serine protease inhibitor Enzyme inhibitory Non-hemolytic

RECORD: Rec_0188963 VERIFIED: YES

Provenance & Taxonomy

OrganismApis cerana [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetB. bassiana

Activity1.4±0.17 μM

MethodIC50

RECORD: Rec_0271731 VERIFIED: YES

Provenance & Taxonomy

OrganismApis cerana [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetB. thuringiensis

Activity1.21±0.095 μM

MethodMIC50

RECORD: Rec_0422274 VERIFIED: YES

Provenance & Taxonomy

OrganismApis cerana [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity2.4±0.18 μM

MethodMIC50