Peptide Database

Peptide NameAntimicrobial peptide microplusin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC423H664N128O142S8

DescriptionStandard

        HQELCTKGDDALVTELECIRLRISPETNAAFDNAVQQLNCLNRACAYRKMCATNNLEQAMSVYFTNEQIKEIHDAATACDPEAHHEHDH
    

Molecular Weight10071.09 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-7.75

Net Charge (pH 7.4) -8.37

Charge Density (pH 7.0) -0.0871

GRAVY Index-0.59

Hydrophobic Moment 0.53

Boman Index-0.10

Instability Index55.25

Aliphatic Index 71.46

Aromaticity 0.0449

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4383.16

LogP -50.52

H-bond Donors 152.0

H-bond Acceptors 148.0

Rotatable Bonds 336.0

Heavy Atoms 701.0

Ring Count 12.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246786 VERIFIED: YES

Provenance & Taxonomy

OrganismRhipicephalus microplus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetMicrococcus luteus

Activity0.38-0.76 μM

MethodMIC