Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC383H595N99O104S8

DescriptionStandard

        MRVLFLIFGVLYLLSTVPPARSFIYIDECPSEYYNCRMKCNADEHAIRYCDDWTICCKLKYIETEKLKRGR
    

Molecular Weight8506.94 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.15

Charge Density (pH 7.0) 0.0216

GRAVY Index-0.12

Hydrophobic Moment 0.56

Boman Index-0.02

Instability Index43.57

Aliphatic Index 87.89

Aromaticity 0.1408

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3284.56

LogP -21.75

H-bond Donors 123.0

H-bond Acceptors 115.0

Rotatable Bonds 278.0

Heavy Atoms 594.0

Ring Count 15.0

Amide Bonds 72.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0229193 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence