Peptide Database

Peptide NamePutative colicin activity protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC468H734N122O136S5

DescriptionStandard

        MRDVQWFCPLTPVHTGTEIKPVEMPVTTITPVSDAGGLQDFIYWRPDADRTGMEPVYVILNDPLDSGRFTRKQLNKNILNMQVILVFSIQE
    

Molecular Weight10405.89 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-3.40

Net Charge (pH 7.4) -3.71

Charge Density (pH 7.0) -0.0374

GRAVY Index-0.15

Hydrophobic Moment 0.55

Boman Index0.07

Instability Index49.35

Aliphatic Index 90.88

Aromaticity 0.0879

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4120.92

LogP -34.61

H-bond Donors 139.0

H-bond Acceptors 139.0

Rotatable Bonds 333.0

Heavy Atoms 731.0

Ring Count 19.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0150153 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0193192 VERIFIED: YES

Provenance & Taxonomy

OrganismShigella flexneri [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0302189 VERIFIED: YES

Provenance & Taxonomy

OrganismShigella flexneri 3a [Bacterium]

FamilyPyocin/Colicin

Tax ID424717

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli