‹ ›
MYP_125871
← PREVIOUS NEXT → BACK
Basic Information
Bac5 (1-17)[F2W; P4,9,17R; Y16W]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C111H177N43O18
Standard
Sequence
RWRRPIRRRPIRPPFWR
Physicochemical Analysis
2401.87 Da
12.00
7.76
7.56
0.4565
-1.91
0.58
-0.83
200.84
45.88
0.1765
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1020.54
-5.93
40.0
26.0
71.0
172.0
9.0
16.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0009240 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal],synthetic construct [Synthetic]
Cathelicidin, Bac5, Proline-rich antimicrobial peptide (PrAMP)
9913;32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
F2W; P4R; P9R; Y16W; P17R
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli SSI-OO15 EIEC
1 μM
MIC
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0011340 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal],synthetic construct [Synthetic]
Cathelicidin, Bac5, Proline-rich antimicrobial peptide (PrAMP)
9913;32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
F2W; P4R; P9R; Y16W; P17R
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli BW25113ΔsbmA
8 μM
MBC
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0036514 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal],synthetic construct [Synthetic]
Cathelicidin, Bac5, Proline-rich antimicrobial peptide (PrAMP)
9913;32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
F2W; P4R; P9R; Y16W; P17R
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli EURL-VTEC C07 STEC:O157
2 μM
MIC
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0038097 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli EA22 ETEC
1 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0060715 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii. ChemMedChem. 2019 Dec 17;14(24):2025-2033. doi: 10.1002/cmdc.201900465. PMID: 31692278. PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
1 2 3 ... 8 NEXT LAST
Showing 5 records on this page · Page 1 of 8