Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC319H502N80O76S9

DescriptionStandard

        MKAPVLLFILFFFLLIVTRANCAMKDTYICFIKKGKCRHECHDFEKPIGFCTKLNANCCL
    

Molecular Weight6962.47 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.61

Net Charge (pH 7.4) 4.17

Charge Density (pH 7.0) 0.0768

GRAVY Index0.52

Hydrophobic Moment 0.50

Boman Index0.17

Instability Index29.61

Aliphatic Index 94.33

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2485.33

LogP -13.31

H-bond Donors 92.0

H-bond Acceptors 92.0

Rotatable Bonds 231.0

Heavy Atoms 484.0

Ring Count 12.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114670 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence