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MYP_125833
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Basic Information
LL-37 KR-12 [R6A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
12 amino acids
C68H119N21O16
Standard
Sequence
KRIVQAIKDFLR
Physicochemical Analysis
1486.80 Da
11.00
2.76
2.55
0.2299
-0.18
0.94
-0.26
31.95
130.00
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
639.65
-3.69
23.0
19.0
53.0
105.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0065808 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 29213
40 μM
MIC
PMID29430821;24307932 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29430821/
RECORD: Rec_0178724 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli K12
40 μM
MIC
PaperStructural location determines functional roles of the basic amino acids of KR-12, the smallest antimicrobial peptide from human cathelicidin LL-37
RECORD: Rec_0198225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
100 μM
Hemolysis
PMID29430821;24307932 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29430821/
RECORD: Rec_0227687 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
human RBC; poor hemo.lytic
>100 μM
HC50
PaperStructural location determines functional roles of the basic amino acids of KR-12, the smallest antimicrobial peptide from human cathelicidin LL-37
RECORD: Rec_0242298 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
40 μM
MIC
PMID29430821;24307932 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29430821/
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