Peptide Database

Peptide NameAcidic phospholipase A2 BmooPLA2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme modulation ▸ Enzyme inhibition ▸ Blood coagulation cascade inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC685H1018N180O210S17

DescriptionStandard

        MRTLWIVAVLLLGVEGNLWQFEMLIMKIAKTSGFLFYSSYGCYCGWGGHGRPQDATDRCCFVHDCCYGKVTGCNPKTDSYTYSEENGDVVCGGDDPCKKQICECDRVAATCFRDNKDTYDNKYWFYPAKNCQEESEPC
    

Molecular Weight15679.60 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-5.45

Net Charge (pH 7.4) -6.02

Charge Density (pH 7.0) -0.0395

GRAVY Index-0.42

Hydrophobic Moment 0.61

Boman Index-0.01

Instability Index38.35

Aliphatic Index 52.25

Aromaticity 0.1377

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 36285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6275.16

LogP -62.54

H-bond Donors 230.0

H-bond Acceptors 224.0

Rotatable Bonds 505.0

Heavy Atoms 1092.0

Ring Count 30.0

Amide Bonds 147.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173547 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops moojeni [Animal]

FamilyPhospholipase A2; Group II subfamily; D49 sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Hydrolase Blood coagulation cascade inhibitor Antiplatelet Toxin Cytotoxic Hypotensive Non-hemolytic

TargetNo Target Organism Found