‹ ›
MYP_125798
← PREVIOUS NEXT → BACK
Basic Information
Mastoparan-R4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C76H145N23O16
Standard
Sequence
INLKKLAARIKKKI
Physicochemical Analysis
1637.11 Da
11.39
5.76
5.54
0.4111
-0.20
0.65
-0.24
-14.97
153.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
676.71
-3.25
24.0
22.0
63.0
115.0
0.0
14.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0073956 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Joker generated [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
human colon adenocarcinoma HT-29
>100 μM
IC50
PaperComputer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties.
RECORD: Rec_0088245 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Joker generated [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
A-baumannii clinical isolate 003326263
>32 μM
MIC
PaperComputer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties.
RECORD: Rec_0089064 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Joker generated [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
E-cloacae clinical isolate 1383251
>32 μM
MIC
PaperComputer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties.
RECORD: Rec_0098634 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
8 %
Hemolysis
PaperPubMed PMID: 31411881 PMID31411881 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31411881/
RECORD: Rec_0113138 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Joker generated [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
human RBC: 8% lysis at 100 uM
>100 μM
HC50
PaperComputer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties.
FIRST PREV 1 2 3 4 ... 7 NEXT LAST
Showing 5 records on this page · Page 2 of 7