Peptide Database

Peptide NameDefensin-like protein 21 (Small protein inhibitor of insect alpha-amylases 2.1), (SI alpha-2.1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Plant bioactivity ▸ Plant defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC208H344N76O62S10

DescriptionStandard

        RVCRRRSAGFKGLCMSDHNCAQVCLQEGWGGGNCDGVMRQCKCIRQC
    

Molecular Weight5222.08 Da

Isoelectric Point (pI)8.97

Net Charge (pH 7.0)4.77

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.1015

GRAVY Index-0.42

Hydrophobic Moment 0.58

Boman Index-0.20

Instability Index83.48

Aliphatic Index 47.66

Aromaticity 0.0426

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2280.73

LogP -30.41

H-bond Donors 89.0

H-bond Acceptors 78.0

Rotatable Bonds 179.0

Heavy Atoms 356.0

Ring Count 4.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386111 VERIFIED: YES

Provenance & Taxonomy

OrganismSorghum bicolor [Animal]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antifungal

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