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MYP_125746
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Basic Information
Opistoporin 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
44 amino acids
C223H355N59O63
Standard
Sequence
GKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNFVAEKIGATPS
Physicochemical Analysis
4870.56 Da
9.78
3.76
3.54
0.0855
-0.54
0.62
-0.03
15.96
77.73
0.0909
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1995.51
-18.03
68.0
67.0
163.0
345.0
9.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0300199 VERIFIED: NO
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperPatent US 7932230 B2 Evidence URLhttps://patents.google.com/patent/US7932230B2/en PatentUS 7932230 B2
RECORD: Rec_0313866 VERIFIED: NO
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0341818 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 38.6%, E 0.0%, T 4.5%, C 56.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0354809 VERIFIED: YES
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
NDBP
Structure & Mods
non-disulfide-bridged amphipathic peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Gram-negative and Gram-positive bacteria
PMID12354111;16036557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0393310 VERIFIED: NO
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
Opistoporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperEur J Biochem. 2002 Oct;269(19):4799-810. | http://www.ncbi.nlm.nih.gov/pubmed/12354111 PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
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