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MYP_125746
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Basic Information
Opistoporin 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
44 amino acids
C223H355N59O63
Standard
Sequence
GKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNFVAEKIGATPS
Physicochemical Analysis
4870.56 Da
9.78
3.76
3.54
0.0855
-0.54
0.62
-0.03
15.96
77.73
0.0909
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1995.51
-18.03
68.0
67.0
163.0
345.0
9.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000580 VERIFIED: YES
Provenance & Taxonomy
African yellow leg [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperAntibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.
RECORD: Rec_0045909 VERIFIED: NO
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
RECORD: Rec_0048329 VERIFIED: YES
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria
PaperPubMed PMID: 12354111 PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0130731 VERIFIED: YES
Provenance & Taxonomy
African yellow [Animal]; Arthropoda [Animal]
33208; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
RECORD: Rec_0266176 VERIFIED: YES
Provenance & Taxonomy
Opistophthalmus carinatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Also has antifungal activity
PaperPubMed PMID: 12354111 PMID12354111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12354111/
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