MYP_125700
hACE2(21-55)F28K-F32E
Standard
35 amino acids
C181H273N47O64
Standard
IEEQAKTKLDKENHEAEDLFYQSSLASWNYNTNIT
4131.38 Da
4.49
-4.14
-4.41
-0.1183
-1.14
0.39
-0.16
74.47
64.29
0.1143
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1856.73
-20.19
62.0
61.0
140.0
292.0
6.0
40.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0008080
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
ACE2-derived
32630
Structure & Mods
lactam-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Ⓚ (8) and Ⓔ (12) are corss-linked by lactam stapling
Bio-Activity Profile
SARS-CoV-2 spike protein-hACE2 complex
46.8 μM
IC50
RECORD: Rec_0022433
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Stapled ACE2-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Severe acute respiratory syndrome coronavirus 2
46.8 μM
IC50
RECORD: Rec_0179359
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Stapled ACE2-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Severe acute respiratory syndrome coronavirus 2
100 μM
IC50