Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC184H281N47O65S5

DescriptionStandard

        MANPFDLDLQSVEVKQGDVQAGSGLICTPGCDEGTFESWCC
    

Molecular Weight4351.80 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-6.53

Net Charge (pH 7.4) -6.81

Charge Density (pH 7.0) -0.1592

GRAVY Index-0.07

Hydrophobic Moment 0.32

Boman Index0.13

Instability Index61.79

Aliphatic Index 64.15

Aromaticity 0.0732

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1786.16

LogP -21.13

H-bond Donors 62.0

H-bond Acceptors 64.0

Rotatable Bonds 140.0

Heavy Atoms 301.0

Ring Count 6.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121420 VERIFIED: NO

Provenance & Taxonomy

OrganismMarininema mesophilum [other]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria