Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC444H710N132O138S14

DescriptionStandard

        MKTSSVAVAVAVVLTFICLQESSAVSFTEVQELEEPMSSEGAVAAFEEMSEESWKMPYNNRHKRSPAGRNSRRRRCRFCCGCCPNMIGCGTCCKF
    

Molecular Weight10554.10 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.52

Net Charge (pH 7.4) 1.10

Charge Density (pH 7.0) 0.0160

GRAVY Index-0.20

Hydrophobic Moment 0.43

Boman Index-0.06

Instability Index106.65

Aliphatic Index 53.37

Aromaticity 0.0737

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4362.53

LogP -52.48

H-bond Donors 163.0

H-bond Acceptors 155.0

Rotatable Bonds 350.0

Heavy Atoms 728.0

Ring Count 13.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381078 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal