Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC472H775N123O137S9

DescriptionStandard

        MKLFLVLIILLFEVPTDGIRPKKCFNNITGYCRKKCKMGEIYESSCRNGKLCCVDEADNKKSKEVLHPPQLAENSNVSLDYMILPTITVSTIQL
    

Molecular Weight10653.53 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)2.54

Net Charge (pH 7.4) 2.15

Charge Density (pH 7.0) 0.0270

GRAVY Index-0.05

Hydrophobic Moment 0.58

Boman Index0.02

Instability Index38.27

Aliphatic Index 99.47

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4201.19

LogP -36.42

H-bond Donors 148.0

H-bond Acceptors 150.0

Rotatable Bonds 362.0

Heavy Atoms 741.0

Ring Count 12.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176562 VERIFIED: NO

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyDefensin

Tax ID9785

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence