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MYP_125594
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Basic Information
Desotamide D
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGNILL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081173 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Human breast adenocarcinoma MCF-7
100 μM
IC50
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0129273 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma NCI-H460
100 μM
IC50
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0252913 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis [Bacterium]
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
X=kynurenine; l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 25072108 PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0259505 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis [Bacterium]
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
X=kynurenine; l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25072108 PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0261574 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis [Bacterium]
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
X=N-formyl-kynurenine; l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25072108 PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
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