‹ ›
MYP_125594
← PREVIOUS NEXT → BACK
Basic Information
Desotamide D
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGNILL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0002649 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
100 μM
IC50
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0006490 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
128 μg/mL
MIC
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0028790 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis [Bacterium]
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
X=N-formyl-kynurenine; l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
100 μM
IC50
PaperPubMed PMID: 25072108 PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0033114 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis SCSIO ZJ46 [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae NCTC 7466
100 μg/mL
MIC
PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
RECORD: Rec_0055245 VERIFIED: YES
Provenance & Taxonomy
Streptomyces scopuliridis [Bacterium]
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
X=kynurenine; l=D-Leu
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
100 μM
IC50
PaperPubMed PMID: 25072108 PMID25072108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25072108/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3