Peptide Database

Peptide NameOpistoporin-1 (OP1) (Non-disulfide-bridged peptide 2.4) (NDBP-2.4) (Non-disulfide-bridged peptide 3.5) (NDBP-3.5) (Opistoporin-3) (OP3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC419H668N104O120S6

DescriptionStandard

        MNRKLLFVTLMVTMLVMQPSEGGKVWDWIKSTAKKLWNSEPVKELKNTALNAAKNLVAEKIGATPSEAGQMPFDEFMDILYE
    

Molecular Weight9274.80 Da

Isoelectric Point (pI)6.26

Net Charge (pH 7.0)-0.48

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0059

GRAVY Index-0.15

Hydrophobic Moment 0.62

Boman Index0.08

Instability Index32.55

Aliphatic Index 86.83

Aromaticity 0.0854

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3605.64

LogP -27.10

H-bond Donors 121.0

H-bond Acceptors 126.0

Rotatable Bonds 313.0

Heavy Atoms 649.0

Ring Count 14.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368512 VERIFIED: YES

Provenance & Taxonomy

OrganismOpistophthalmus carinatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria