Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length471 amino acids

Chemical FormulaC2396H3773N585O698S16

DescriptionStandard

        MKVSITFLILGLFILLLEANPGIKVKITQKALDYGNQFGVELLKQKLKGKTFEDWNGESTYWFFALNYTISKIRIDNMELPNTSLSLISGTGIKLLVENASAIATADWSVETWLFKDSGSAAVFISGVNLTAIVNVSQNVFGHLKLSLDSCKADVDDMDIKLNQSYRWLYTYSTASLVKSLCSMLATNLCPQVNFVIQKINKDFSQYPVQAQVGNFAVIDYSLINSSTILESSINLDLKGTVYPVEEITEPPFKPTPFVLLNENNSMFYIGISEYLLQSASLAYFTSGAFTISAEQEEMLSSYFKLTTDTLESIIPTISHIHAKPLPVIMNIRITDAPVISLYDNKSILKFSASMEVLAKMPNSTTQSMFTLNITTRTHADLTIFNRRLLTTLCLNSFHSSLAHSNVGLFEASLLDNFLSYILRTGIIPAANFKLKDGFPLPALDPMILMKPSIRIYEGFLLISTDIQSLR
    

Molecular Weight52455.13 Da

Isoelectric Point (pI)5.76

Net Charge (pH 7.0)-4.98

Net Charge (pH 7.4) -5.67

Charge Density (pH 7.0) -0.0106

GRAVY Index0.22

Hydrophobic Moment 0.68

Boman Index0.18

Instability Index30.42

Aliphatic Index 107.88

Aromaticity 0.1019

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51590.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270670 VERIFIED: NO

Provenance & Taxonomy

OrganismPantherophis guttatus (Corn snake) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria