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MYP_125562
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Basic Information
Distinctin Peptide A-A homodimer
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
22 amino acids
C114H196N32O30S
Standard
Sequence
ENREVPPGFTALIKTLRKCKII
Physicochemical Analysis
2527.04 Da
9.79
2.83
2.64
0.1285
-0.17
0.64
-0.08
28.09
106.36
0.0455
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1016.85
-7.42
36.0
34.0
85.0
177.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0304418 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
There is an intermolecular disulphide bridge between Distinctin chain 1 (Cys19) and Distinctin chain 2 (Cys22). There is an intermolecular disulphide bridge between Distinctin chain 1 (Cys19) and Distinctin chain 2 (Cys22)
Bio-Activity Profile
Antimicrobial
Note: Distinctin chain 1 links to Distinctin chain 2 to form a heterodimeric peptide to exert antibacterial function
PaperPubMed PMID: 19189273 PMID19189273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19189273/
RECORD: Rec_0304511 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
There is an intermolecular disulphide bridge between Distinctin chain 1 (Cys19) and Distinctin chain 2 (Cys22). There is an intermolecular disulphide bridge between Distinctin chain 1 (Cys19) and Distinctin chain 2 (Cys22)
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
28 μM
MIC
PaperPubMed PMID: 19189273 PMID19189273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19189273/
RECORD: Rec_0330838 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPDB 1XKM structural record; NMR; chain A/C; residues 1-22
RECORD: Rec_0368855 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
There is an intermolecular disulphide bridge between Distinctin chain 1 (Cys19) and Distinctin chain 2 (Cys22). There is an intermolecular disulphide bridge between Distinctin chain 1 (Cys19) and Distinctin chain 2 (Cys22)
Bio-Activity Profile
Antimicrobial
Escherichia coli
14.5 μM
MIC
PaperPubMed PMID: 19189273 PMID19189273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19189273/
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