Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC609H997N173O189S3

DescriptionStandard

        MVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHT
    

Molecular Weight13862.67 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-3.31

Net Charge (pH 7.4) -3.64

Charge Density (pH 7.0) -0.0240

GRAVY Index0.15

Hydrophobic Moment 0.77

Boman Index0.16

Instability Index53.54

Aliphatic Index 97.68

Aromaticity 0.0145

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5600.80

LogP -65.42

H-bond Donors 182.0

H-bond Acceptors 191.0

Rotatable Bonds 425.0

Heavy Atoms 974.0

Ring Count 22.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400780 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli