Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC373H606N112O101S13

DescriptionStandard

        MEKRCMALVLLLLLLLAPQEVVWRIEGRMCESQSHKFHGLCMSDRTCVVVCKEEDFDDGKCRGFRHRCFCRKPC
    

Molecular Weight8692.34 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)2.69

Net Charge (pH 7.4) 2.17

Charge Density (pH 7.0) 0.0363

GRAVY Index-0.10

Hydrophobic Moment 0.57

Boman Index-0.10

Instability Index61.26

Aliphatic Index 78.92

Aromaticity 0.0676

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3437.27

LogP -28.54

H-bond Donors 131.0

H-bond Acceptors 120.0

Rotatable Bonds 296.0

Heavy Atoms 599.0

Ring Count 11.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176841 VERIFIED: NO

Provenance & Taxonomy

OrganismEucalyptus grandis [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence