Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length116 amino acids

Chemical FormulaC611H944N156O174S10

DescriptionStandard

        MNLLMLTFIICGFLNLVTKAGWTVERCWKNNIGHCRKRCFHVERYKLLCMNKLTCCIPIKEDHGYTKTPPRLIPFEEEITTDINTWEFFSNSPASFLNDEFIPDSTKPIESLETET
    

Molecular Weight13579.62 Da

Isoelectric Point (pI)5.90

Net Charge (pH 7.0)-2.28

Net Charge (pH 7.4) -2.79

Charge Density (pH 7.0) -0.0197

GRAVY Index-0.22

Hydrophobic Moment 0.60

Boman Index0.03

Instability Index40.06

Aliphatic Index 79.83

Aromaticity 0.1121

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5287.95

LogP -42.84

H-bond Donors 188.0

H-bond Acceptors 185.0

Rotatable Bonds 443.0

Heavy Atoms 951.0

Ring Count 26.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419123 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyDefensin

Tax ID9713

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence