Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC924H1401N215O280S8

DescriptionStandard

        IDDLAKVDYSLNSFPAVLQPFINLDLKGTVYPSGNHTGPSYVAAPFVIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISREIFGSIIPEVREYSVTPYPVMLKLMATEIPIISLQQDSFTVEIQGSMEAFAVLPDSTTQSLFTINMAANTSIAPNIFDQKLMGSLCLNR
    

Molecular Weight20257.80 Da

Isoelectric Point (pI)4.17

Net Charge (pH 7.0)-11.15

Net Charge (pH 7.4) -11.48

Charge Density (pH 7.0) -0.0609

GRAVY Index0.21

Hydrophobic Moment 0.52

Boman Index0.22

Instability Index48.16

Aliphatic Index 90.11

Aromaticity 0.1311

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7846.32

LogP -85.73

H-bond Donors 266.0

H-bond Acceptors 278.0

Rotatable Bonds 643.0

Heavy Atoms 1427.0

Ring Count 37.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354022 VERIFIED: NO

Provenance & Taxonomy

OrganismRamphastos sulfuratus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria