Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC740H1163N217O218S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQALRSLLVELKVQYAGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16811.93 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0133

GRAVY Index-0.37

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index40.51

Aliphatic Index 76.16

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7024.34

LogP -71.95

H-bond Donors 247.0

H-bond Acceptors 233.0

Rotatable Bonds 561.0

Heavy Atoms 1182.0

Ring Count 26.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078621 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage KP32_isolate 195 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic