MYP_125365
Diketopiperazine (preWW)
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antiviral
▸
Anti-Hepatitis virus
▸
Immunology
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Immune modulation
▸
Immunomodulatory activity
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
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Cytotoxicity
▸
Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
XW
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0005984
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
A2780
89.7 μM
IC50
RECORD: Rec_0059332
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
Tumor cells: K562
29.8 μM
IC50
RECORD: Rec_0091375
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Immunomodulatory dipeptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
γ-glutamyl linkage
Bio-Activity Profile
Anti-HCV
Immunomodulatory
Hepatitis C virus
RECORD: Rec_0104828
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
RECORD: Rec_0264474
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
A2780-cisR
80.8 μM
IC50
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