Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length140 amino acids

Chemical FormulaC721H1137N195O202S14

DescriptionStandard

        MRPVSSWLREISAVHISECDTQPHRHLRNCCLGCSFFSPNQFFFKLLMDLYFIDLFTCADAMRPKKCFSNVTGFCRKRCKLGETSDKGCLRGKFCCVNLEENKKYKKAPEVPDEHFTQNEKDKVEEVVILPTVTLITIIL
    

Molecular Weight16217.84 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.14

Charge Density (pH 7.0) 0.0269

GRAVY Index-0.21

Hydrophobic Moment 0.82

Boman Index-0.04

Instability Index41.41

Aliphatic Index 77.21

Aromaticity 0.1000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6396.71

LogP -56.18

H-bond Donors 231.0

H-bond Acceptors 224.0

Rotatable Bonds 542.0

Heavy Atoms 1132.0

Ring Count 26.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219595 VERIFIED: NO

Provenance & Taxonomy

OrganismIctidomys tridecemlineatus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence