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MYP_125326
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Basic Information
Hemoglobin alpha chain [067-106]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
40 amino acids
C199H323N55O59
Standard
Sequence
TKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLL
Physicochemical Analysis
4430.03 Da
5.97
-2.25
-2.65
-0.0561
-0.06
0.51
0.06
13.28
126.75
0.0250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1803.36
-14.95
61.0
61.0
147.0
313.0
7.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017410 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Enzyme inhibitory Anti-Gram-positive Anti-Gram-negative
Escherichia coli
35 μM
MIC
RECORD: Rec_0071283 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Hemoglobin alpha-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli; Listeria innocua
MIC
Papera 67-106 of bovine hemoglobin: a new family of antimicrobial and angiotensin I-converting enzyme inhibitory peptides | Adje, E. et al. | DOI: 10.1007/s00217-011-1430-z Evidence URLhttps://www.uniprot.org/uniprotkb/P01966/entry
RECORD: Rec_0232599 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Enzyme inhibitory Anti-Gram-positive Anti-Gram-negative
Listeria innocua
35 μM
MIC
RECORD: Rec_0236619 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
35 μM
MIC
PMID21510973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21510973/
RECORD: Rec_0335979 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Enzyme inhibitory Anti-Gram-positive
Micrococcus luteus
141 μM
MIC
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