Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length583 amino acids

Chemical FormulaC2689H4265N811O858S10

DescriptionStandard

        MSGGDGIGHNSGAHSTGGVNGSSSGRGGSSSGGGNNPNSGPGWGTTHTPDGHDIHNYNPGEFGGGGHKPGGNSGNHSDGTGDGQPSGAAMAFGFPALVPAGAGGLAVTVSGDALAAAIADVLAVLKGPFKFGVWGIALYGILPTEIAKDDPRMMSKIATSLPADAVTESPVSSLPLGQATISVTKRVTDVVKDERQHIAVVAGVPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNAPAMTALPRGVTDEKDRTVDPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHLVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQAEFNAAEKEKADADAALNVALESRKQKEQKAKDASDKLDKENKRNHPGKATGKGQPVGDKWLEDAGKEAGAPVPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPELSKQFIKGNRDRMQVGKAPKSRKSDAAGKRTSFELHHDKPISQDGGVYDMDNIRVTTPKHHIDIHRGK
    

Molecular Weight62003.20 Da

Isoelectric Point (pI)7.06

Net Charge (pH 7.0)0.25

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) 0.0004

GRAVY Index-0.69

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index34.39

Aliphatic Index 63.48

Aromaticity 0.0515

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295536 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella houtenae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic

TargetEscherichia coli