Peptide Database

Peptide NameTachyplesin-1 (Tachyplesin I)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC402H638N118O121S9

DescriptionStandard

        MKKLVIALCLMMVLAVMVEEAEAKWCFRVCYRGICYRRCRGKRNEVRQYRDRGYDVRAIPEETFFTRQDEDEDDDEE
    

Molecular Weight9348.67 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-2.52

Net Charge (pH 7.4) -2.84

Charge Density (pH 7.0) -0.0327

GRAVY Index-0.65

Hydrophobic Moment 0.67

Boman Index-0.26

Instability Index40.78

Aliphatic Index 68.31

Aromaticity 0.1039

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3951.65

LogP -32.88

H-bond Donors 146.0

H-bond Acceptors 128.0

Rotatable Bonds 320.0

Heavy Atoms 650.0

Ring Count 10.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320829 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyTachyplesin polyphemusin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria