Peptide Database

Peptide NameP6(ACE2 (4-26)-G-ACE2 (333-339))

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC161H236N42O53

DescriptionStandard

        EEQAKTFLDKFNHEAEDLFYQSSGLGKGDFR
    

Molecular Weight3607.85 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-3.07

Net Charge (pH 7.4) -3.30

Charge Density (pH 7.0) -0.0990

GRAVY Index-1.06

Hydrophobic Moment 0.54

Boman Index-0.16

Instability Index56.86

Aliphatic Index 44.19

Aromaticity 0.1613

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1576.25

LogP -15.80

H-bond Donors 53.0

H-bond Acceptors 51.0

Rotatable Bonds 124.0

Heavy Atoms 256.0

Ring Count 6.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405434 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyACE2-derived peptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antiviral

TargetSevere acute respiratory syndrome coronavirus

Activity0.1 μM

MethodIC50

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