Peptide Database

Peptide NameCecropin A

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC184H315N55O45S

DescriptionStandard

        RWKVFKKIEKMGRNVRDGIIKAGPAIAVLGEAKALGK
    

Molecular Weight4049.88 Da

Isoelectric Point (pI)10.71

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1827

GRAVY Index-0.20

Hydrophobic Moment 0.89

Boman Index-0.06

Instability Index36.86

Aliphatic Index 100.27

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1640.75

LogP -11.65

H-bond Donors 58.0

H-bond Acceptors 53.0

Rotatable Bonds 144.0

Heavy Atoms 285.0

Ring Count 4.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0002299 VERIFIED: YES

Provenance & Taxonomy

OrganismTrichoplusia ni [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)