Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC440H698N122O122S9

DescriptionStandard

        MKLLYLFLAILLVIEEPVISGKRHILRCMGNSGICRASCKRNEQPYLYCRNYQSCCLQSYMRISISGKEENTDWSYEKQWPRLP
    

Molecular Weight9937.58 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)4.54

Net Charge (pH 7.4) 4.15

Charge Density (pH 7.0) 0.0540

GRAVY Index-0.31

Hydrophobic Moment 0.66

Boman Index-0.06

Instability Index87.01

Aliphatic Index 88.21

Aromaticity 0.1071

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3976.39

LogP -33.46

H-bond Donors 146.0

H-bond Acceptors 137.0

Rotatable Bonds 331.0

Heavy Atoms 693.0

Ring Count 16.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277128 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Bacterium]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence