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MYP_125210
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Basic Information
Macropin 1 [L6Aca]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GFGMAXKLLKKVL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus subtilis 168
1.3 μM
MIC
PMID24616110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24616110/
RECORD: Rec_0103977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human lymphoblastic leukemia CCRF-CEM
9
IC50
PMID24616110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24616110/
RECORD: Rec_0105027 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6
Bio-Activity Profile
Hemolytic
human erythrocytes
93 μM
Hemolysis
PMID24616110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24616110/
RECORD: Rec_0107772 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human colon adenocarcinoma SW480
18
IC50
PMID24616110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24616110/
RECORD: Rec_0111286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human cervical carcinoma HeLa S3
8
IC50
PMID24616110 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24616110/
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