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MYP_125147
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Basic Information
Coleoptericin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
74 amino acids
C353H543N115O107
Standard
Sequence
SLQGGAPNFPQPSQQNGGWQVSPDLGRDDKGNTRGQIEIQNKGKDHDFNAGWGKVIRGPNKAKPTWHVGGTYRR
Physicochemical Analysis
8109.79 Da
10.11
4.64
4.31
0.0626
-1.32
0.68
-0.21
43.88
42.16
0.0811
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3630.81
-46.61
121.0
114.0
266.0
575.0
17.0
86.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0275631 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
coli D22 (highly activity)
PaperPubMed PMID: 1761552 PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/
RECORD: Rec_0316689 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperBulet P., Cociancich S., Dimarcq J.-L., Lambert J., Reichhart J.-M., Hoffmann D., Hetru C., Hoffmann J.A.;. "Insect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family."; J. Biol. Chem. 266:24520-24525. Evidence URLhttps://www.uniprot.org/uniprotkb/COLE_ZOPAT/entry
RECORD: Rec_0337744 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli D31
PaperPubMed PMID: 1761552 PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/
RECORD: Rec_0385343 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Coleoptericin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
A. baumanii
PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/
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