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MYP_125147
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Basic Information
Coleoptericin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
74 amino acids
C353H543N115O107
Standard
Sequence
SLQGGAPNFPQPSQQNGGWQVSPDLGRDDKGNTRGQIEIQNKGKDHDFNAGWGKVIRGPNKAKPTWHVGGTYRR
Physicochemical Analysis
8109.79 Da
10.11
4.64
4.31
0.0626
-1.32
0.68
-0.21
43.88
42.16
0.0811
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3630.81
-46.61
121.0
114.0
266.0
575.0
17.0
86.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009270 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Coleoptericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Biol Chem. 1991 Dec 25;266(36):24520-5. | http://www.ncbi.nlm.nih.gov/pubmed/1761552 PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/
RECORD: Rec_0014536 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Coleoptericin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
P. maltophilia
PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/
RECORD: Rec_0028422 VERIFIED: NO
Provenance & Taxonomy
Zophobas atratus [Animal]
Coleoptericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-negative Hemolytic Non-ribosomal
Gram-negative bacteria
Qualitative functional evidence
PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/; https://www.uniprot.org/uniprotkb/P80032/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0031391 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
PaperPubMed PMID: 1761552 PMID1761552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1761552/
RECORD: Rec_0095629 VERIFIED: YES
Provenance & Taxonomy
Zophobas atratus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli D31
PaperInsect immunity. Isolation from a coleopteran insect of a novel inducible antibacterial peptide and of new members of the insect defensin family.
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