Peptide Database

Peptide Namechemerin

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length134 amino acids

Chemical FormulaC689H1086N204O197S6

DescriptionStandard

        ELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLACIKLGSEDKVLGRLVHCPIETQVLREAEEHQETQCLRVQRAGEDPHSFYFPGQF
    

Molecular Weight15571.63 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)3.25

Net Charge (pH 7.4) 2.69

Charge Density (pH 7.0) 0.0242

GRAVY Index-0.72

Hydrophobic Moment 0.59

Boman Index-0.18

Instability Index59.35

Aliphatic Index 68.36

Aromaticity 0.0821

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6501.03

LogP -61.68

H-bond Donors 228.0

H-bond Acceptors 211.0

Rotatable Bonds 521.0

Heavy Atoms 1096.0

Ring Count 27.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364089 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Chemotactic Immunomodulatory Signaling peptide

Targetchemerin receptor 1 (Human); chemerin receptor 2 (Human); CCRL2 (Human)

Activity3-4.5 nM

MethodEC50