Peptide Database

Peptide NameBmKDfsin4-F2A/F6A analog

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC169H270N62O48S6

DescriptionStandard

        GAGCPANQGQCHKHCQSIRRRGGYCDGFLKTRCVCYR
    

Molecular Weight4130.73 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)5.87

Net Charge (pH 7.4) 5.47

Charge Density (pH 7.0) 0.1587

GRAVY Index-0.77

Hydrophobic Moment 0.58

Boman Index-0.26

Instability Index64.83

Aliphatic Index 34.32

Aromaticity 0.0811

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1811.61

LogP -24.32

H-bond Donors 71.0

H-bond Acceptors 62.0

Rotatable Bonds 136.0

Heavy Atoms 285.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141642 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAPD analysis reveals that this sequence is similar (94.59%) to BmKDfsin4 C=G: 16%; R: 14%. Chemical modification: 3 disulfide bonds

Bio-Activity Profile

Function

Antimicrobial

TargetStaphylococcus epidermidis AB208187 or AB208188

Activity2 μM

MethodMIC