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MYP_125121
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Basic Information
Z44
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C108H200N30O31
Standard
Sequence
ALSKALSKALSKALSKALSKALSK
Physicochemical Analysis
2414.93 Da
10.70
5.79
5.59
0.2412
0.23
0.61
0.00
9.58
122.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1010.12
-11.33
37.0
37.0
89.0
169.0
0.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0111532 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Xenopus laevis
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
CHP-100
Trypan blue assay
PaperAntibiotic magainins exert cytolytic activity against transformed cell lines through channel formation PMID1708887;2285300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1708887/
RECORD: Rec_0112557 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Magainin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-937
97 μg/mL
IC50
PaperPubMed PMID: 1708887 PMID1708887 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1708887/
RECORD: Rec_0118424 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Xenopus laevis
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
MCF-7
Trypan blue assay
PaperAntibiotic magainins exert cytolytic activity against transformed cell lines through channel formation PMID1708887;2285300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1708887/
RECORD: Rec_0155892 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Xenopus laevis
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
MLA
102 μg/mL
IC50
PaperAntibiotic magainins exert cytolytic activity against transformed cell lines through channel formation PMID1708887;2285300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1708887/
RECORD: Rec_0156780 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Xenopus laevis
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
PC-3
Trypan blue assay
PaperAntibiotic magainins exert cytolytic activity against transformed cell lines through channel formation PMID1708887;2285300 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1708887/
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